Idera Pharmaceuticals (NASDAQ: IDRA) this morning announced the successful completion of the phase 1 portion of the ongoing phase 1/2 clinical trial of intratumoral IMO-2125 for the treatment of anti-PD-1 refractory metastatic melanoma. Enrollment has commenced for the phase 2 portion of the trial, and Idera expects to have overall response rate (ORR) data available in the first quarter of 2018. “There is a very clear unmet medical need for those patients for whom current checkpoint inhibitor therapies are not providing adequate solutions. We are incredibly focused on advancing this program as rapidly as possible for these patients, and we are also looking forward to exploring areas outside of melanoma in which intratumoral IMO-2125 may also serve an important role through its unique mechanism of action within the tumor microenvironment,” CEO Vincent Milano stated in the news release.
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About Idera Pharmaceuticals
Idera Pharmaceuticals is a clinical-stage biopharmaceutical company developing novel nucleic acid-based therapies for the treatment of certain cancers and rare diseases. Idera’s proprietary technology involves designing synthetic oligonucleotide-based drug candidates to modulate the activity of specific TLRs. In addition to its TLR programs, Idera has used its proprietary knowledge to create a third generation antisense technology platform which inhibits the production of disease-associated proteins by targeting RNA. To learn more about Idera, visit www.iderapharma.com.
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