Heat Biologics, Inc. (NASDAQ: HTBX) this morning said Natasa Strbo, M.D., D.Sc., research assistant professor of Microbiology and Immunology at the University of Miami Miller School of Medicine, has received a three-year $981,901 grant from the Florida Department of Health 2016-17 Zika Research Grant Initiative to further develop and test the gp96-based Zika vaccine. The vaccine is being developed under a collaboration between the University of Miami and Heat’s wholly owned subsidiary, Zolovax, Inc., which has licensed the patent. The grant is expected to cover the preclinical development of the Zika vaccine, and allow Dr. Strbo to expand her laboratory staff. “This validation is further evidence that Dr. Strbo is on the right track in targeting Zika with our gp96-based vaccine, and why we are working with the University of Miami to develop it,” Heat’s founder and CEO Jeff Wolf stated in the news release.
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About Heat Biologics, Inc.
Heat Biologics, Inc. (NASDAQ: HTBX) is an immuno-oncology company developing novel therapies that are designed to activate a patient’s immune system against cancer utilizing an engineered form of gp96, a protein that activates the immune system when cells die. Heat’s highly specific T cell-stimulating therapeutic vaccine platform technologies, ImPACT and ComPACT, in combination with other therapies, such as checkpoint inhibitors, are designed to address three distinct but synergistic mechanisms of action: robust activation of CD8+ “killer” T cells (one of the human immune system’s most potent weapons against cancer); reversal of tumor-induced immune suppression; and T cell co-stimulation to further enhance patients’ immune response. Currently, Heat is conducting a Phase 2 trial with HS-110 (viagenpumatucel-L) in combination with an anti-PD-1 checkpoint inhibitor to treat patients with non-small cell lung cancer (NSCLC) and a Phase 2 trial with HS-410 (vesigenurtacel-L) in patients with non-muscle invasive bladder cancer (NMIBC). Heat’s wholly-owned subsidiary, Zolovax, Inc., is developing therapeutic and preventative vaccines to treat infectious diseases based on Heat’s gp96 vaccine technology, with a current focus on the development of a Zika vaccine in conjunction with the University of Miami. For more information, please visit www.heatbio.com.
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