NetworkNewsBreaks – TapImmune, Inc. (NASDAQ: TPIV) Receives Positive DSMB Safety Review for TPIV 200, Advances Phase 2 Trial

TapImmune (NASDAQ: TPIV) this morning said it has received a positive recommendation from an independent Data Safety Monitoring Board (DSMB) regarding the company’s lead cancer vaccine candidate, TPIV 200, to continue dosing triple-negative breast cancer (TNBC) patients in an ongoing phase 2 clinical trial. The planned safety review was conducted when enrollment was at 25 percent (20/80 patients). The four-arm trial is designed to test the safety, dosing level and optimal treatment regimen of TPIV 200 against TNBC cells. TapImmune will enroll the remaining patients at 12 clinical centers in the U.S., with enrollment completion targeted for the end of 2017. “This is now our second TPIV 200 clinical study to complete a successful interim safety review allowing the continuation of recruitment according to the protocol. Our Phase 2 clinical trial in platinum-resistant ovarian cancer at Memorial Sloan Kettering Cancer Center, in combination with Astra-Zeneca’s durvalumab, had previously passed its initial safety review and this study has now recruited over 50 percent of total patients. We have two additional Phase 2 trials now enrolling or about to enroll ovarian and triple-negative breast cancer patients, and continue to believe TPIV 200 will have a significant impact in the cancer immunotherapy space. We look forward to bringing this product to these ovarian and breast cancer patients in need of advanced therapy in the most expeditious manner possible,” TapImmune chairman and CEO Dr. Glynn Wilson stated in the news release.

To view the full press release, visit:

About TapImmune, Inc.

TapImmune, Inc. is an immuno-oncology company specializing in the development of innovative technologies for the treatment of cancer, including metastasis, and infectious disease. The company’s peptide or nucleic acid-based immunotherapeutics, comprise one or multiple naturally processed epitopes (NPEs) designed to comprehensively stimulate a patient’s killer T-cells, helper T-cells and to restore or further augment antigen presentation by using proprietary nucleic acid-based expression systems. The company’s technologies may be used as stand-alone medications or in combination with current treatment modalities. For more information, visit the company’s website at

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